???????

2016312?й??????й???????????????????????á??????е岻?г????

?

??2011

?????壨EGFR??????С??NSCLC???????????????С??NSCLC??????

?????????λС????з?80%?75%?????5????С??С???????м???

2014???????61,160?м?50.08%29.78%20.15%?2014???2012~2014??-0.51%-9.35%87.78%

?2011Уги??????Ч??С????????о????QALY??Ч???С?????25/QALY35/QALY46/QALY

?QALY??,?????

??

??

??2008

??????????????

??????2.9?и??2.7??з?20%????????75????????????H ?????H ????????Ч????????????з?

????????ATC4 C09AA￡20122.24%г?2015?7.03%20125.57%2015?4.05%??2012~2014???67.5%????????

??2009???2013???????????

??

?

??2014

????????AMD

?AMD?50???????仯????,????????(AMD) ????AMD?????AMD?Σ

?AMD??10???仯?? (VEGF)??????AMD????????????VEGF??У鵥???

?鵥?????3+Q3M3+PRN?Ч鵥3+Q1MЧ???????????????????????y鵥65%

????????棬?п?鵥г???20149.18%20.39%201410.82%25.59%

???????Ч????????á???????δ???????谭

????????????????з???????????????ο?????λ????????

??й??????