201679? /BIOON/ --??￡Gilead??μβ?Epclusa??????棬FDAμ?Epclusa?6??ΡEpclusa??????EC??6??Ρ
???Epclusa????Ψ????????????????3sofosbuvir?Τ????Epclusa???2?3ε????Τ?Epclusa????????FDAEpclusa????
Epclusa??1Epclusa?12???д??Child-Pugh A?λ?2EpclusaΤ?RBV12?????Child-Pugh BC?λ?
Epclusasof/vel400mg/100mg???ε??μβ??6??GT-1,-2,-3,-4,-5,-6λ??üβ?е??Sovaldisofosbuvir???velpatasvirɡУsofosbuvir?????velpatasvir??NS5A?
Epclusasof/vel??4IIIASTRAL?о??Що?6??GT-1,-2,-3,-4,-5,-6?SOF/VELЧ????üβ?6???Чд?????塣4оУ1035?λ?12???98%SVR12?SVR12?12?????????12?HCV RNA??????θ??
Epclusa????λ??
Epclusasof/vel??2??????DAAs???μβ??????1?????Χ????λ??Ρ???ε????????Ч??????ε3HCV?
Epclusasof/vel???μβ??μ???SovaldiHarvoniγ????????ε??????λ????
???Epclusasof/vel????μβ?
??±?2?SovaldiHarvoni2?????μ???λ???2014??μβ?±?????85%г?䶮
Epclusasof/vel?μ3sofosbuvir??μβ???????????μβ?У?±?????п???????Bioon.com
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